Omeprazole Induced Acute Interstitial Nephritis in an Adolescent
نویسندگان
چکیده
Proton pump inhibitors (PPIs) have emerged as a common cause of drug induced acute interstitial nephritis (AIN) in adults. We present a 15-year-old girl with severe acute kidney injury and biopsy proven AIN attributable to omeprazole. Withdrawal of the drug and steroid therapy affected a recovery of renal function. As the use of PPIs increases in paediatrics, it is important to be aware of this rare but serious side effect.
منابع مشابه
Acute interstitial nephritis secondary to esomeprazole.
The Medical Journal of Australia ISSN: 0025729X 7 March 2005 182 5 235-236 ©The Medical Journal of Australia 2005 www.mja.com.au Lessons from practice nephritis induced by esomeprazole, along with six renal failure and two of renal impairment. In October 2004, the manufacturer of esomep Zeneca, reported being aware of at least 15 cases acute interstitial nephritis possibly induced by esom at le...
متن کاملDrug-induced tubulo-interstitial nephritis secondary to proton pump inhibitors: experience from a single UK renal unit.
BACKGROUND Acute tubulo-interstitial nephritis (TIN) is an important cause of acute renal failure, and is often caused by hypersensitivity to drugs. The aim of this study was to determine the aetiology of interstitial nephritis among an unselected cohort of patients, and to identify those drugs commonly implicated. METHODS A single-centre retrospective analysis was carried out of renal biopsy...
متن کاملHypercalcaemia and acute interstitial nephritis associated with omeprazole therapy.
Keywords: acute interstitial nephritis; acute renal fail-1+ proteinuria. There was no clinical evidence of foetal ure; hypercalcaemia; omeprazole distress. Omeprazole therapy was commenced.
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متن کاملنفریت بینابینی حاد ناشی از پنتوپرازول: گزارش موردی
Pantoprazole is a proton-pump inhibitor that is commonly prescribed for the treatment of gastroesophageal reflux-related disorders. Acute interstitial nephritis is an uncommon though important side-effect of these classes of drugs. We reported a case with acute interstitial nephritis due to pantoprazole. A 25-year-old woman from Ardabil was admitted to our hospital with the complaint of fever, ...
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تاریخ انتشار 2014